E could attack brain disease Alzheimers, study shows
As taken from Daily Nutrition News Yahoo,Dec. 1997
They said if their method
worked in people, it could offer a new approach to treating Alzheimer's
disease and other diseases that come from damage to brain cells.
This is because vitamin C
is a powerful antioxidant, working to prevent the damage caused
by everyday life, damage that leads to diseases such as cancer,
heart disease, and perhaps even Alzheimer's.
"We now know how to get
large amounts of an antioxidant into the brain," Dr. David
Agus, a cancer specialist at Memorial Sloan-Kettering Center
in New York, said in a statement.
Some recent studies have shown
that vitamin E, another strong antioxidant, can work against
In April 1997 a team at New
York's Columbia University found that both vitamin E and the
anti-Parkinson's drug selegiline appeared to delay for six to
seven months the milestones of the disease, such as required
institutionalization, inability to perform basic activities of
living, severe dementia and death.
Vitamin C might be another
candidate for helping prevent cell damage, but when people take
vitamin C orally, most of it is lost in the urine and wasted,
because it dissolves in water.
Agus's team looked at how
vitamin C gets into the brain naturally. Reporting in the Journal
of Clinical Investigation, it said it had found that cells could
break the vitamin down into ascorbic acid and dehydroascorbic
Cells use vitamin C in the
form of ascorbic acid.
The researchers injected mice
with both forms, killed them and looked at their brains. They
found that the mice injected with dehydroascorbic acid had more
ascorbic acid in their brain cells afterward.
"Our findings from this
study have therapeutic implications, because we can potentially
increase vitamin C concentrations in the brain by increasing
the blood level of dehydroascorbic acid," Dr. David Golde,
who also worked on the study, said.
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